nir irradiation Search Results


nir-irradiated nanoprobes  (Nanoprobes Inc)
90
Nanoprobes Inc nir-irradiated nanoprobes
Nir Irradiated Nanoprobes, supplied by Nanoprobes Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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nir-irradiated nanoprobes - by Bioz Stars, 2026-04
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laser irradiation in the nir-ii  (BioWindow Gene Development Inc)
90
BioWindow Gene Development Inc laser irradiation in the nir-ii
Laser Irradiation In The Nir Ii, supplied by BioWindow Gene Development Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/laser irradiation in the nir-ii/product/BioWindow Gene Development Inc
Average 90 stars, based on 1 article reviews
laser irradiation in the nir-ii - by Bioz Stars, 2026-04
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nir laser irradiation (bohr-808-fcir8  (Xi'an Tianlong Science)
90
Xi'an Tianlong Science nir laser irradiation (bohr-808-fcir8
Nir Laser Irradiation (Bohr 808 Fcir8, supplied by Xi'an Tianlong Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nir laser irradiation (bohr-808-fcir8/product/Xi'an Tianlong Science
Average 90 stars, based on 1 article reviews
nir laser irradiation (bohr-808-fcir8 - by Bioz Stars, 2026-04
90/100 stars
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nir irradiation  (Niron Magnetics)
90
Niron Magnetics nir irradiation
Nir Irradiation, supplied by Niron Magnetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nir irradiation/product/Niron Magnetics
Average 90 stars, based on 1 article reviews
nir irradiation - by Bioz Stars, 2026-04
90/100 stars
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uv and nir irradiations  (Photonics Inc)
90
Photonics Inc uv and nir irradiations
Uv And Nir Irradiations, supplied by Photonics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/uv and nir irradiations/product/Photonics Inc
Average 90 stars, based on 1 article reviews
uv and nir irradiations - by Bioz Stars, 2026-04
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nir-irradiator  (Thorlabs)
90
Thorlabs nir-irradiator
Nir Irradiator, supplied by Thorlabs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nir-irradiator/product/Thorlabs
Average 90 stars, based on 1 article reviews
nir-irradiator - by Bioz Stars, 2026-04
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nir laser irradiation lrd 808  (Laserglow Technologies)
90
Laserglow Technologies nir laser irradiation lrd 808
Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and <t>NIR</t> laser <t>irradiation.</t> (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.
Nir Laser Irradiation Lrd 808, supplied by Laserglow Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nir laser irradiation lrd 808/product/Laserglow Technologies
Average 90 stars, based on 1 article reviews
nir laser irradiation lrd 808 - by Bioz Stars, 2026-04
90/100 stars
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980-nm nir irradiation laser  (Changchun New Industries Optoelectronics)
90
Changchun New Industries Optoelectronics 980-nm nir irradiation laser
Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and <t>NIR</t> laser <t>irradiation.</t> (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.
980 Nm Nir Irradiation Laser, supplied by Changchun New Industries Optoelectronics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/980-nm nir irradiation laser/product/Changchun New Industries Optoelectronics
Average 90 stars, based on 1 article reviews
980-nm nir irradiation laser - by Bioz Stars, 2026-04
90/100 stars
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consists of silica nps coated with a gold shell (auroshell®) that are activated by nir irradiation  (Nanospectra Biosciences)
90
Nanospectra Biosciences consists of silica nps coated with a gold shell (auroshell®) that are activated by nir irradiation
Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and <t>NIR</t> laser <t>irradiation.</t> (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.
Consists Of Silica Nps Coated With A Gold Shell (Auroshell®) That Are Activated By Nir Irradiation, supplied by Nanospectra Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/consists of silica nps coated with a gold shell (auroshell®) that are activated by nir irradiation/product/Nanospectra Biosciences
Average 90 stars, based on 1 article reviews
consists of silica nps coated with a gold shell (auroshell®) that are activated by nir irradiation - by Bioz Stars, 2026-04
90/100 stars
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nir irradiation  (Photonics Inc)
90
Photonics Inc nir irradiation
Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and <t>NIR</t> laser <t>irradiation.</t> (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.
Nir Irradiation, supplied by Photonics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nir irradiation/product/Photonics Inc
Average 90 stars, based on 1 article reviews
nir irradiation - by Bioz Stars, 2026-04
90/100 stars
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flame-s vis-nir 350-1000 downwelling irradiance sensor  (Ocean Insight)
90
Ocean Insight flame-s vis-nir 350-1000 downwelling irradiance sensor
Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and <t>NIR</t> laser <t>irradiation.</t> (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.
Flame S Vis Nir 350 1000 Downwelling Irradiance Sensor, supplied by Ocean Insight, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/flame-s vis-nir 350-1000 downwelling irradiance sensor/product/Ocean Insight
Average 90 stars, based on 1 article reviews
flame-s vis-nir 350-1000 downwelling irradiance sensor - by Bioz Stars, 2026-04
90/100 stars
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nir laser irradiation (808 psu-iii-lrd)  (Changchun New Industries Optoelectronics)
90
Changchun New Industries Optoelectronics nir laser irradiation (808 psu-iii-lrd)
Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and <t>NIR</t> laser <t>irradiation.</t> (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.
Nir Laser Irradiation (808 Psu Iii Lrd), supplied by Changchun New Industries Optoelectronics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nir laser irradiation (808 psu-iii-lrd)/product/Changchun New Industries Optoelectronics
Average 90 stars, based on 1 article reviews
nir laser irradiation (808 psu-iii-lrd) - by Bioz Stars, 2026-04
90/100 stars
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Image Search Results


Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and NIR laser irradiation. (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.

Journal: ACS Nano

Article Title: Targeted Therapeutic Nanotubes Influence the Viscoelasticity of Cancer Cells to Overcome Drug Resistance

doi: 10.1021/nn501223q

Figure Lengend Snippet: Drug-resistant cell treatment by CD44-targeted sSWCNT drug delivery and NIR laser irradiation. (A, B) OVCAR8/ADR cells were treated with free DOX or CAHA-sSWCNT-DOX and assessed for apoptosis (broken DNA fragments are labeled green) and cell membrane integrity (intact cell membranes are labeled green) using (A) TUNEL (apoptosis) and (B) Calcein AM (live cell) assays. Cells were treated with free DOX, CAHA-sSWCNTs, or CAHA-sSWCNT-DOX for 6 h and then irradiated with an 808 nm NIR laser probe at 0.5 W/cm 2 for 2.5 min. Cells were further incubated for 48 h and then fixed and stained for apoptosis with the TUNEL assay and for live cells using the Calcein AM assay. Green indicates positive for the assays, with cell nuclei stained blue using DAPI. (C–F) Percentage of viable cells after exposure to CAHA, CAHA-sSWCNTs, free DOX, PEG-sSWCNT-DOX, or CAHA-sSWCNT-DOX (DOX concentration adjusted to IC 50 values of free DOX (OVCAR8 ∼2.1 μM and OVCAR8/ADR ∼150 μM without irradiation and OVCAR8 ∼1.5 μM and OVCAR8/ADR ∼100 μM with irradiation). (C) Cell viability in the absence of NIR laser irradiation ([DOX] = 2.1 μM). CAHA and CAHA-sSWCNTs are not cytotoxic. (D) Resistance factor (RF) of CAHA-sSWCNT-DOX (∼7.6) compared to the free drug (∼71.1) calculated by taking ratios of respective IC 50 values of drug-resistant and drug-sensitive cells. (E) Cell viability of cancer cells irradiated with an 808 nm laser at 1 W/cm 2 for 2.5 min ([DOX] = 1.5 μM). The photothermal and photodynamic effects of CAHA-sSWCNTs in addition to DOX treatment led to very effective killing of both OVCAR8 and OVCAR8/ADR cells by CAHA-sSWCNT-DOX. (F) RF of CAHA-sSWCNT-DOX (∼1.3) compared to the free drug (∼66.7). **, p < 0.01; ***, p < 0.001.

Article Snippet: OVCAR8/ADR cells were grown to 60–70% confluency and then treated with the appropriate formula for 6 h. The cells were then washed and subjected to 808 nm NIR laser irradiation (LRD 808, Laserglow Technologies, CA, USA).

Techniques: Irradiation, Labeling, Membrane, TUNEL Assay, Incubation, Staining, Calcein AM Assay, Concentration Assay

In vivo MDR tumor targeting by CD44-targeted CAHA-sSWCNT drug delivery and NIR irradiation system. (A) Thermal imaging of OVCAR8/ADR tumor xenograft exposed to an 808 NIR laser 24 h post CAHA-sSWCNT-DOX administration. (B) Eradication of pre-established OVCAR8/ADR MDR xenografts ( n = 6/group) by a single CAHA-sSWCNT-DOX treatment (12 mg/kg DOX equivalent) followed by NIR laser irradiation (1 W/cm 2 , 90 s).

Journal: ACS Nano

Article Title: Targeted Therapeutic Nanotubes Influence the Viscoelasticity of Cancer Cells to Overcome Drug Resistance

doi: 10.1021/nn501223q

Figure Lengend Snippet: In vivo MDR tumor targeting by CD44-targeted CAHA-sSWCNT drug delivery and NIR irradiation system. (A) Thermal imaging of OVCAR8/ADR tumor xenograft exposed to an 808 NIR laser 24 h post CAHA-sSWCNT-DOX administration. (B) Eradication of pre-established OVCAR8/ADR MDR xenografts ( n = 6/group) by a single CAHA-sSWCNT-DOX treatment (12 mg/kg DOX equivalent) followed by NIR laser irradiation (1 W/cm 2 , 90 s).

Article Snippet: OVCAR8/ADR cells were grown to 60–70% confluency and then treated with the appropriate formula for 6 h. The cells were then washed and subjected to 808 nm NIR laser irradiation (LRD 808, Laserglow Technologies, CA, USA).

Techniques: In Vivo, Irradiation, Imaging

Histology of tumor mice treated with CAHA-sSWCNT-DOX. Hematoxylin and eosin (H&E) staining of tumors and primary organs of OVCAR8/ADR tumor xenograft bearing mice treated with CAHA-sSWCNT-DOX along with controls and exposed to 808 nm NIR irradiation 24 h post-treatment. (A) Saline with PTT, (B) free DOX with PTT, (C) CAHA-sSWCNT-DOX without PTT, (D) CAHA-sSWCNTs alone with PTT, and (E) CAHA-sSWCNT-DOX with PTT. Scale bar = 10 μm.

Journal: ACS Nano

Article Title: Targeted Therapeutic Nanotubes Influence the Viscoelasticity of Cancer Cells to Overcome Drug Resistance

doi: 10.1021/nn501223q

Figure Lengend Snippet: Histology of tumor mice treated with CAHA-sSWCNT-DOX. Hematoxylin and eosin (H&E) staining of tumors and primary organs of OVCAR8/ADR tumor xenograft bearing mice treated with CAHA-sSWCNT-DOX along with controls and exposed to 808 nm NIR irradiation 24 h post-treatment. (A) Saline with PTT, (B) free DOX with PTT, (C) CAHA-sSWCNT-DOX without PTT, (D) CAHA-sSWCNTs alone with PTT, and (E) CAHA-sSWCNT-DOX with PTT. Scale bar = 10 μm.

Article Snippet: OVCAR8/ADR cells were grown to 60–70% confluency and then treated with the appropriate formula for 6 h. The cells were then washed and subjected to 808 nm NIR laser irradiation (LRD 808, Laserglow Technologies, CA, USA).

Techniques: Staining, Irradiation, Saline